ENDOMETRIOSIS
It affects 1 in 10 women and is typically manifested by severe menstrual pain, pain during sexual intercourse or chronic pelvic pain. The prevalence of endometriosis in women with infertility can be as high as 40%.
DIAGNOSIS OF ENDOMETRIOSIS
Typically spanning from a few years to over a decade, the diagnostic process has thus far proven to be extremely difficult with the use of the currently available diagnostic methods (symptom-based medical history, ultrasound examination, limited access to MRI examinations and their inconclusive results or invasive laparoscopy not being recommended as diagnostic method).
EndoRNA qRT-PCR
Is an innovative, minimally invasive laboratory test for diagnosing endometriosis. It allows for early diagnosis and quicker access to specialised treatment.
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0 mln
women worldwide suffer from endometriosis
0 years
the average time needed to diagnose endometriosis using currently available methods
0 days
the average time needed to diagnose endometriosis using the innovative EndoRNA test

MINIMALLY INVASIVE MEDICAL DEVICE

EndoRNA qRT-PCR represents a breakthrough in the diagnosis of endometriosis. Its use allows early diagnosis and quicker initiation of specialised treatment. EndoRNA test result supports healthcare professionals in further diagnosis and treatment decisions.

EndoRNA qRT-PCR is a test intended for quantitative measurement of the relative level of the expression of the FUT4 gene – a marker for endometriosis. In the test, FUT4 mRNA data are expressed relative to the GAPDH reference gene. The analysis is performed on the endometrial tissue sample collected from a patient in the secretory phase of the menstrual cycle to confirm or exclude endometriosis.

DIAGNOSTIC PROCESS

01

Sample collection

A sample is obtained by aspiration biopsy with a Pipelle catheter.

02

Transport to the laboratory

The sample is transported to the laboratory in an RNA preservation solution.

03

Analysis

mRNA extraction and measurement of the FUT4 expression

Małoinwazyjny test laboratoryjny

PRODUCT ADVANTAGES

After the sample collection, the patient can resume her normal routines

Quick diagnostic process, even within 48 hours from the sample collection (depending on the laboratory workload), while it may take up to 8 years today.

Following the coronavirus pandemic, PCR technology became globally accessible

EndoRNA test is a registered medical device

Quick diagnosis enables healthcare professionals to provide treatment sooner

Other currently available markers, such as CA 125 or Bcl6, are not specific for endometriosis

DIAGNOSTIC EFFICienCY

A ratio of true positive results to the sum of true positive and false negative results

Sensitivity / Czułość diagnostyczna

Specificity / Swoistość diagnostyczna

Positive predictive value (PPV)

Negative predictive value (NPV)

Accuracy

Probability index

Youden index

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